🚀 Postdoctoral Research Scientist

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The tumor microenvironment lab, part of ONCOMET, at the Health Research Institute of Santiago de Compostela (IDIS), is looking for a postdoctoral researcher to join our team.

Our group studies new therapeutic strategies in high grade gliomas based on biophysical strategies, with a particular focus on the immune and non-immune tumor microenvironment.

We are located at the University Clinical Hospital of Santiago de Compostela, and we have a daily and fluent connection with the Medical Oncology, Neurosurgery, Radiotherapy and Neuroimaging clinical departments, which makes our research highly translational.

About the project

The GlioProof project, funded in the private-public collaboration call (AEI), will be developed in close collaboration with Batea Oncology, a startup developing therapeutic solutions for Glioblastoma patients, as well as with 3 leading hospitals in Spain.

The project has a strong clinical orientation, as it aims at bringing a biomaterial-based therapeutic strategy to a Phase I clinical trial in Glioblastoma patients.

As well, we will perform fundamental/translational research in order to deepen into the mechanisms of action of such biomaterials, as well as in exploring new potential therapeutic combinations.

Tasks

• Perform 2D/3D in vitro assays with biomaterials and cellular models, including primary glioma organoids.
• Develop new potential models.
• Monitor cell behaviour applying flow cytometry, advanced microscopy, RNA-Seq and proteomic based techniques, among others.
• Perform in vivo experiments, including orthotopic glioma models (mice and rats, immunocompetent and immunodeficient), or others.
• Study the combined effects of biomaterial implants with radiation/chemotherapy or immunotherapies.
• Analyze patient-derived samples (tissue and blood) from patients recruited in the Phase I trial.
• Actively collaborate with other projects in the lab, as well as with national and international partners.

Requirements

• PhD in cancer biology, biotechnology, bioengineering or related field.
• Experience with cell culture, primary cell culture/organoids will be an asset.
• Demonstrated experience with animal models.
• Having an active animal experimentation license is a must.
• Fast learning and able to conduct experiments independently.
• Good writing data plotting skills.
• Presentation skills will be valued.
• Strong organizational skills, working comfortably in a fast-paced environment.
• Easy-going, collaborative, enthusiastic, proactive person, able to work in multidisciplinary environments.
• Fluent in English, Spanish is an asset but not required.

What do we offer?

You will be part of a young, dynamic and supportive lab environment.

The possibility to work on a genuinely translational project, and take an active part on the development of a phase I clinical trial, in collaboration with a startup.

2 year working contract, competitive salary based on experience.

Expected starting date: January ****

How to apply

Send your CV with experience and publications, motivation letter, and 2 references with contact information to ******.

Applications not including all this information will not be considered.

Deadline to apply: November 15th ****

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Seniority level: Internship

Employment type: Contract

Job function: Research

Industries: Sporting Goods Manufacturing

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